- Towards Colonial Freedom (1947)
- His first major work, written while in Britain, calling for independence across Africa.
- Autobiography of Kwame Nkrumah (1957)
- Published the same year Ghana gained independence; details his early life, struggles, and political journey.
- I Speak of Freedom: A Statement of African Ideology (1961)
- Outlines his Pan-African vision and strategy for African unity and liberation.
- Africa Must Unite (1963)
- Advocates political and economic unity as the path to Africa’s strength and progress.
- Consciencism: Philosophy and Ideology for Decolonization (1964)
- His philosophical work, presenting his ideology for a liberated Africa, blending traditional African values with socialism.
- Neo-Colonialism: The Last Stage of Imperialism (1965)
- Critiques Western exploitation of Africa even after independence; controversial and opposed by Western powers.
- Challenge of the Congo (1967)
- Examines the Congo crisis, imperialism, and betrayal of African independence efforts.
- Dark Days in Ghana (1968)
- A reflection on the 1966 coup that overthrew his government, analyzing causes and consequences.
- Voice from Conakry (1967–1972, published posthumously)
- Collection of his broadcasts and writings while in exile in Guinea.
- Handbook of Revolutionary Warfare (1968)
- A practical guide for African liberation movements, emphasizing armed struggle against colonialism.
- Class Struggle in Africa (1970)
- Explores the role of class in African politics and calls for socialist revolution.
- Revolutionary Path (1973, posthumous)
- A compilation of his writings, speeches, and reflections on revolution and Pan-Africanism.
- Rhodesia File (1975, posthumous)
- Focuses on the liberation struggle in Rhodesia (now Zimbabwe).
These works are not just political manifestos but form the foundation of Nkrumahism, his enduring philosophy of African unity, socialism, and anti-imperialism.